A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Killedar, S. G.
- Anthelmintic and Anti-Insect Activities of Memecylon umbellatum Burm Root Extracts
Authors
1 Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Near Chitranagari, Kolhapur- 416 013 (M.S.), IN
2 Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur, M. S., IN
Source
Research Journal of Pharmacology and Pharmacodynamics, Vol 2, No 1 (2010), Pagination: 52-56Abstract
Different extracts of Memecylon umbellatum Burm ischolar_main were screened for Anthelmintic and anti-insect activities using Indian earthworms (Pheretima posthuma) and red flour beetle, Tribolium castaneum (Herbst) respectively. The acetone and methanolic extracts exhibited significant (p<0.01) anthelmintic and anti-insect activities compared with the control and other extracts. Albendazole and Piperazine citrate were used as standards for anthelmintic activity while Neem Extract, Celphos (Aluminium phosphide) and citronellal for anti-insect activity. Chloroform, ethyl acetate and aqueous extracts showed weak activities. Acetone ischolar_main extract showed most promising Anthelmintic activity at 20mg/mi compare to albendazole and insecticidal activity at 10mg concentration comparable to standard celphos (5%). Further investigations are however necessary to explore mechanism(s) of action involved in these pharmacological activities and constituents responsible for both the activities.Keywords
Memecylon umbellatum, Anthelmintic, Anti-Insect, Pheretima posthuma, Tribolium castaneum.References
- Zettler JL, Cuperus GW, Pesticide resistance in Tribolium castaneum (Coleoptera:tenebrionidae) and Rhizoptera dominica (Coleoptera:Bostrichidae) in wheat. 1990; J EconEnt. 3:1677.
- Zettler JL, Pesticide resistance in Tribolium castaneum and Tribolium confusum (coleopteran:Tenebrionidae) from flour mills in the USA. 1991; J Econ Ent. 84:763.
- Khambay BPS, Beddie DG, Simmonds MSJ. Phytochemistry. 2002; 59:69.
- Gonzalez CA et al. J Agric Food Chem. 1999; 47 (10):4419.
- Meena R et al. J Med Arom Plant Sci. 1999; 21 (4):1043.
- Govindachari T.R. Chemical and Biological Investigation on Azadirachta indica. Curr sci. .1992; 63 (3):117-122.
- Schmutterer H. Properties and Potential of Natural Pesticide from the Neem tree, Azadirachta indica. Ann Rev Ent. 1990; 35:271-297.
- Kirtikar KR and Basu BD. Indian Medicinal Plants, Popular Prakashan, New Delhi. 1996; 2nd
- Nadkarni KM. Indian Materia Medica, Bombay Prakashan, Bombay. 1982; pp. 787.
- Sastri BN. The Wealth of India, Publication and Information Directorate, CSIR. Hillside, New Delhi, India. 1962; pp. 336.
- Dhar ML et al. Screening of Indian plants for biological activity:Part 1. Indian J. Exp. Biol. 1968; 2:232-247.
- Amalraj T and Ignacimuthu S. Evaluation of Hypoglycemic effect of Memecylon umbellatum in normal and alloxan diabetic mice. J Ethanopharmacol. 1998; 62:247-250.
- Joshi H. et al. Hypoglycemic effect of Memecylon umbellatum ischolar_main. PHCOG MAG. 2008; 15:1-4.
- Puratchikody and Naglakshmi G. Wound Healing Activity of Memecylon umbellatum burm. J Plant Sci. 2007; 2:179-186.
- Ram PR and Mehrotra BN. Compendium of Indian Medicinal Plants, (Drug Research Preparative:A CDRI Series):VOL. 2, Central Drug Research Institute, Lucknow and Publications and Information Directorate, New Delhi. 1993; pp:453.
- Asolkar LV, Kakkar KK and Chakre OJ. Glossary of Indian Medicinal Plants with active principles, part-I. Publications and Information Directorate, Council of Scientific and Industrial Research Publ, New Delhi. 1956; pp:165.
- Kokate CK. Practical Pharmacognosy, 1st ed:Vallabh Prakashan New Delhi. 1985; pp:111-115.
- Harborne JB. Phytochemical methods:A Guide to modern techniques of plant Analysis, 2nd ed:Chapman and Hall, New York. 1984; pp:85.
- Khandelwal KR. Practical Pharmacognosy Techniques and Experiments, Nirali Prakashan, Pune. 2nd ed:2000; 149-156.
- Ghosh T, Maity TK, Bose A, and Dash GK. Anthelmintic activity of Bacopa monnieri. Indian J Nat.Prod. 2005; 21:16-19.
- Thorn GW, Adams RD, Braunwald E, Isselbacher KJ, Petersdorf RG, Harrison's Principle of internal Medicine. Mcgraw Hill Co., New York. 1977; pp:1088.
- Vigar Z. Atlas of Medical Parasitology, 2nd ed:P. G. Publishing House, Singapore. 1984; pp:216.
- Kokate CK, Purohit AP, Gokhale SB. 'Pharmacognosy Nirali Prakashan, Pune. 39th ed:2007; pp:129.
- Talukder FA, Howse PE. Deterrents and Insecticidal Effects of Extracts of Pithraj, Aphanamixis polystachya (Meliaceae) against Tribolium castaneum (herbst). J chem. Eco. 1993; 19:2463-2471.
- Hashim MS, Devi KS. Insecticidal action of the polyphenolic rich fractions from the stem bark of Streblus asper on Dysdercus cingulatus. Fitoterapia. 2003; 74:670-676
- Loganathan J, Dhingra S, Walia S. Efficiency of Pongamia glabra Vent. Extracts on Feeding and Development of Spodoptera litura (Fabricius). Pestic Res J. 2006; 18 (1):15-19.
- Samarasinghe MKSRD, Chhilar BS and Singh R. Insecticidal Properties of Methanolic Extract of Allium sativum L. and its Fractions against Plutella xylostella (L.) Pestic Res J. 2007; 19 (2):145-148.
- Harborne JB. Plant Phenolics. In:Harborne JB, editor. Methods in Plant Biochemistry. Academic Press Ltd., 1989; pp:227.
- Kim DH, Ahn YJ. Pest Manage Sci. 2001; 57 (3):301.
- Schneider C et al. Phytochemistry. 2000; 54 (8):731.
- Khambay BP, Beddie DG, Simmonds MSJ. J Natl Prod. 1999; 62(10):1423.
- Schmutterer H. Properties and Potential of Natural Pesticide from the Neem tree, Azadirachta indica Ann Rev Ent. 1990; 35:271-297.
- Miyazawa M, Nakamura Y, Ishikawa YJ Agric Food Chem. 2000; 48 (8):3639.
- Pereda MR, Bernard CB, Durst T, Arnason JT, Sanchez VP, Poveda L, San RL. Insecticidal activity of Piper guanacastensis against A. atropalpus mosquito larvae J Natl Prod. 2008.
- Standardization and Antimicrobial Activity of Watery Fluid at Floral Base of Spathodea campanulata (Pal)
Authors
1 Bharati Vidyapeeth College of Pharmacy, Kolhapur (M.S.), IN
Source
Asian Journal of Pharmaceutical Analysis, Vol 1, No 1 (2011), Pagination: 19-21Abstract
Traditionally seeds, bark, leaves of Spathodea campanulata Pal are used as laxative and antiseptic. Bark is also used for swollen cheeks and cleaning newly born babies. Molluscicidal, antioxidant and anti malarial activities of bark are reported. Central wood is toxic and used for hunting wild animals by Uganda tribes. Flower base contains watery fluid and no scientific data available on this fluid hence the present work was undertaken to evaluate the watery fluid and its medicinal properties.
Fresh flowers were collected locally early in the morning then punctured at base with pointed needle and fluid was collected in cleaned screw cap bottles. The collected fluid was then subjected for stability studies. Fluid was analyzed for viscosity, density, pH, florescent analysis and total solid content using standard official methods. Mineral content was determined by acid digestion method using atomic absorption. Watery fluid was studied for secondary metabolites by TLC studies. Antimicrobial activity was performed by cup plate method against selected strains of bacteria and fungi. The watery fluid was found stable up to 48h and six months in atmospheric condition and at refrigeration respectively. The viscosity, density and pH were found to be 0.8645cp, 0.9426g/ml and 6.4 respectively. Undiluted fluid has shown milky, greenish and yellowish green fluorescence at short, long and day wavelengths respectively. Total dissolved solids were found to be 3.15% w/v and sedimentation time was 2h. Mineral contents found were Ca, Mg, Fe, Cr, Zn, Mn, Ni. TLC studies showed presence of steroids with blue fluorescence at Rf 0.9, and 0.7. Dried residue has showed good antibacterial activity against all the tested organisms but had shown weak antifungal activity.
Keywords
Standardization, Antimicrobial Activity, Spathodea campanulata, Watery Fluid, Floral Base.- Formulation and Evaluation of Herbal Lipstick using Lycopene Extracted from Solanum lycopersicum L
Authors
1 Department of Pharmaceutics, Bharati Vidyapeeth College of Pharmacy, Kolhapur-416013, MS, IN
2 Department of Pharmacognosy, Bharati Vidyapeeth College of Pharmacy, Kolhapur-416013, MS, IN
3 Department of Pharmaceutical Chemistry, Bharati Vidyapeeth College of Pharmacy, Kolhapur-416013, MS, IN